Today, neurological diseases are one of the most important factor which causes death. Including the deadly nerve disorders, neurological diseases can be noted Zellweger syndrome. This disease autosomal recessive inheritance pattern is transferred to the next generation. The disease is caused by mutations in genes in nerve cells. But epigenetic factors also have an important role in the ability to induce the disease. In this study we have analyzed 20 people. 10 patients Zellweger syndrome and 10 persons control group. The genes PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, or PEX26, were analyzed in terms of genetic mutations. In this study, people who have genetic mutations were targeted, with nervous disorders, Zellweger syndrome. In fact, of all people with Zellweger syndrome. 10 patients Zellweger syndrome had a genetic mutations in the genes PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, PEX26 Zellweger syndrome. Any genetic mutations in the target genes control group were not show. This is Last Gene.

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Shahin Asadi,student of Molecular Genetics, Studied Molecular Biology at Tabriz Islamic Azad University Sciences.BS.Moleculer and Cellular Biology-Genetics,MS.c Moleculer Biology and Genetics Director of research, nuclear researcher of the National Center for Genetic Engineering and Biotechnology in Iran.